The clinical formulation is supplied in a sterile form for intravenous use only. Include information regarding the recommendation of liver function tests. Syringes containing this product must be labelled, using the auxiliary sticker provided, to state. This patient package insert does not take the place of talking to your doctor about your medical condition or treatment. For the treatment of acute leukemia for the treatment of hodgkins disease. Each ml contains 1 mg vincristine sulfate, usp, 100 mg.
Highlights of prescribing information these highlights do not include allthe information needed to use hycamtinfor injection safely and effectively. This is not a complete list of side effects and others may occur. Y36511411 contraindications warnings vincristine sulfate. Side effects of vincristine sulfate injection vincristine. Vials of vinblastine sulfate for injection usp contain 10 mg. Vinblastine sulfate can cause fetal harm when administered to a pregnant woman. The products discussed may have different product labeling in other countries. The risk of cardiomyopathy is further increased with concomitant cardiotoxic therapy. This medication is to be used as directed by the physician. The mechanism of action of vincristine sulfate has been related to the inhibition of microtubule formation in the. This product information is intended only for residents of the united states. Monitor hepatic function and interrupt, reduce, or discontinue dosing as recommended see warnings and precautions 5.
Vincristine sulfate injection is usually used with other chemotherapy drugs to slow or stop cancer cell growth. Any use of the information is subject, at all times, to ccos terms and conditions. Marqibo vincristine sulfate acrotech biopharma llchighlights of prescribing information these highlights do not include all the information needed to use marqibo vincristine sulfate liposome injection safely and effectively. Only select registry of toxic effects of chemical substances rtecs data is presented here. Xgeva denosumab injection, for subcutaneous use initial u. See full prescribing information for marqibo vincristine sulfate liposome injection. Vincristine sulfate injection is a cancer chemotherapy drug used to treat various types of cancer. You can ask your pharmacist or doctor for information about diflucan that is written for health professionals. Highlights of prescribing information do not coadminister. Nov 09, 2018 vincristine is cancer medication that interferes with the growth of cancer cells and slows their spread in the body. A protocol using cyclophosphamide in place of nitrogen mustard and vinblastine sulfate instead of vincristine sulfate is an alternative therapy for previously untreated patients with advanced hodgkins disease. Vincristine sulfate injection, usp is a sterile, preservativefree, singledose only solution available for intravenous use in 2 ml 1 mg and 2 mg vials. Animal studies with vinblastine sulfate suggest that teratogenic effects may occur.
Highlights of prescribing information patients at risk of. Vincristine side effects, dosage, interactions drugs. Alimta pemetrexedfor injection, for intravenous use initial u. Each ml contains 1 mg vincristine sulfate, usp, 100 mg mannitol and water for injection, usp. Should you require information related to the management of side effects. Mar 01, 2020 vincristine sulfate injection, usp is a sterile, preservativefree, singledose only solution available for intravenous use in 2 ml 1 mg and 2 mg vials. Call your doctor for medical advice about side effects. See full prescribing information for rituxan hycela. Vincristine sulfate is an oncolytic vinca alkaloid. Highlights of prescribing information these highlights do not include all the information needed to use truxima safely and effectively.
Pdr drug summaries are concise pointofcare prescribing, dosing and administering information to help phsyicans more efficiently and accurately prescribe in their practice pdr s drug summaries are available free of charge and serve as a great resource for us based mds, dos, nps and pas in patient practice. Highlights of prescribing information these highlights do not. Highlights of prescribing information these highlights do not include all the information needed to use. See full prescribing information for afinitorafinitor disperz. Vincristine side effects, dosage, interactions drugs everyday health search. Dosing and administration brochure please see pages 2427 and accompanying full prescribing information, including boxed warnings and medication guide, for rituxan hycela important safety information. Owners should be advised of the potential for adverse reactions, including anaphylaxis, and be informed of the clinical signs associated with drug toxicity see warnings, precautions and adverse reactions sections. Report any adverse reaction experiences while taking this medication. Highlights of prescribing information these highlights do not include all the information needed to use alimta safely and effectively. Concomitant administration of azole antifungals, including noxafil, with vincristine has been associated with. Safety and efficacy of rolapitant for prevention of chemotherapyinduced nausea and vomiting after administration of cisplatinbased highly emetogenic chemotherapy in patients with cancer. Verify drug name and dose prior to preparation and administration to avoid overdosage. There is insufficient information on the excretion of vincristine sulfate in human milk. In 98% ethanol, vincristine sulfate, usp has an ultraviolet spectrum with maxima at 221 nm.
The risk of cardiomyopathy is further increased with concomitant. This product is a sterile solution for canceroncolytic use. Highlights of prescribing information these highlights do not include all the information needed to use besponsa safely and effectively. Refer to the prescribing information for a rituximab product for intravenous infusion for additional information. Injection of vincristine sulfate injection, usp should be accomplished within 1 minute. Highlights of prescribing information truxima rituximababbs. Mar 09, 2020 vincristine sulfate injection, usp is a sterile, preservativefree, singledose only solution available for intravenous use in 2 ml 1 mg and 2 mg vials. Wellbutrin bupropion hydrochloride tablets, for oral use. Fatal and serious hypersensitivity reactions including anaphylaxis have occurred in patients receiving feraheme. In intact tectal plates from mouse embryos, vinorelbine, vincristine and vinblastine inhibited mitotic microtubule formation at the same concentration 2 m, inducing a blockade of cells at metaphase.
Highlights of prescribing information these highlights do not include all the information needed to use xgeva safely and effectively. Mabthera in combination with methotrexate is indicated for the treatment of adult patients with severe active rheumatoid arthritis who have had an inadequate response or intolerance to other diseasemodifying antirheumatic drugs dmard including one or more tumour necrosis factor. Vincristine sulfate injection, usp is a sterile, preservativefree, single use only solution available for intravenous use in 2 ml 1 mg and 2 mg vials. Highlights of prescribing information these highlights do not include all the information needed to use erbituxsafely and effectively. For basic information on the current brand used at the bc cancer agency, see chemotherapy preparation. Only administer feraheme as an intravenous infusion over at. Vincristine binds reversibly to spindle proteins in s phase. Truxima rituximababbs injection, for intravenous use initial u. Highlights of prescribing information these highlights do not include all the information needed to use velcade safely and effectively.
Hepatotoxicity has been observed in clinical trials and postmarketing experience. Erbituxcetuximabinjection,for intravenous use initial u. Highlights of prescribing information these highlights do not include all the information needed to use rituxan hycela safely and effectively. Talk to your doctor if you have any questions about folotyn. Afinitor everolimus tablets, for oral use afinitor disperz everolimus tablets for oral suspension. Marqibo vincristine sulfate liposome injection for intravenous infusion.
Marqibo vincristine sulfate liposome injection has different dosage recommendations than vincristine sulfate injection. Highlights of prescribing information ideation, suicide. Feraheme is an iron replacement product indicated for the treatment of iron deficiency anemia ida in adult patients. Full prescribing information pdf download download the full prescribing information. Dec 01, 2019 caution is necessary with the administration of all oncolytic drugs during pregnancy.
Premedicate before each dose of rituxan hycela see dosage and administration 2. Information on the use of vinblastine sulfate during human pregnancy is very limited. Pfizer for professionals 18005054426 the product information provided in this site is intended only for healthcare professionals in the united states. Matulane is used as part of the mopp nitrogen mustard, vincristine, procarbazine, prednisone regimen. Sulfuric acid or sodium hydroxide have been added for ph control. Velcade bortezomib for injection, for subcutaneous or intravenous use initial u. Vincristine sulfate vincristine sulfate this product information is intended only for residents of the united states. Vincristine fda prescribing information, side effects and uses. Highlights of prescribing information these highlights do not include all the information needed to use tarceva safely and effectively. You can also visit the diflucan internet site at lab038010. This leaflet summarizes the most important information about diflucan. Vincristine is a naturally occurring vinca alkaloid. These highlights do not include all the information needed to use wellbutrin safely and effectively.
Etopophos etoposide phosphate for injection, for intravenous use. Severe local tissue necrosis will occur if there is extravasation during administration. Initial symptoms may include hypotension, syncope, unresponsiveness, cardiaccardiorespiratory arrest. See full prescribing information for hycamtinfor injection.
Rituxan hycela rituximab and hyaluronidase human injection, for subcutaneous use initial u. These highlights do not include all the information needed to use etopophos safely and effectively. Venofer is indicated for the treatment of iron deficiency anemia in patients. Vincristine fda prescribing information, side effects. Vincristine sulfate investigated as a drug, mutagen, reproductive effector, and tumorigen. Vinorelbine injection usp should be administered under the supervision of a physician experienced in the use of cancer chemotherapeutic agents.
Highlights of prescribing information these highlights do not include all the information needed to use noxafil safely and effectively. Vincristine comes as a solution liquid to be injected intravenously into a vein by a doctor or nurse in a medical facility. Vinblastine fda prescribing information, side effects and uses. For intravenous use only fatal if given by other routes 5. Hepatotoxicity may be severe, and in some cases fatal. Read the full patient package insert that comes with folotyn before you start treatment and each time you get treated with folotyn. Vincristine sulfate vincristine sulfate dose, indications. It is freely soluble in water, soluble in methanol, and slightly soluble in ethanol. Prescribing information pdf open prescribing information.
Patients using megestrol acetate should receive the following instructions. Highlights of prescribing information these highlights do not include all the information needed to use afinitorafinitor disperz safely and effectively. Specialty therapy access resources star is a reimbursement support, copay assistance, and patient assistance program designed to help patients and healthcare professionals in the united states gain appropriate access to the following products. If you would like more information, talk with your doctor. Department of health and human services public health.
Adriamycin must not be given by the intramuscular or subcutaneous route. For intravenous use only fatal if given by other routes death has occurred with intrathecal use marqibo vincristine sulfate liposome injection has different dosage recommendations than vincristine sulfate injection. A sterile solution of vincristine sulfate 1 milligramml and mannitol 100. Jan 17, 2020 see full prescribing information for complete boxed warning. See pdf for full patient package insert for folotyn. Sep 16, 2008 our vincristine sulfate injection side effects drug center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Vinblastine fda prescribing information, side effects. Intrathecal administration of other vinca alkaloids has resulted in death. See actual entry in rtecs for complete information. See full prescribing information for complete boxed warning. Product monograph prvincristine sulfate injection usp. Clinical pharmacology the mechanisms of action of vincristine sulfate remain under investigation. Please see full prescribing information for matulane indications and usage, contraindications, and warnings including boxed warnings, precautions, and adverse reactions.
Highlights of prescribing information perforation can occur. Noxafil posaconazole injection, for intravenous use noxafil posaconazole delayedrelease tablets, for oral use noxafil posaconazole oral suspension. Myocardial damage can occur with doxorubicin hydrochloride with incidences from 1% 20% for cumulative doses from 300 mgm 2 to 500 mgm 2 when doxorubicin hydrochloride is administered every 3 weeks. Serious irreversible myocardial toxicity with delayed congestive. Treatment of patients following intrathecal administration of vincristine has included. Highlights of prescribing information these highlights do. Marqibo vincristine sulfate liposome dose, indications. Click here for information to how to obtain the product.
Vincristine sulfate injection, usp should not be given to patients while they are receiving radiation therapy through ports that include the liver. The brand name of vincristine sulfate injection is discontinued, but generic versions may be available. Vincristine sulphate 1 mgml injection summary of product characteristics smpc by hospira uk ltd. Dose reductions of rituxan hycela are not recommended. Fda approved indication vincristine sulfate is indicated. Patients are calculated based on an estimated annual cumulative dose. The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you have.